02 August 2010
Presentation of the Genetic Toxicology Laboratory of IPL
The Genetic Toxicology Laboratory of IPL has extensive experience in genotoxicity studies and offers the core battery of genotoxicity tests in compliance with Good Laboratory Practice regulations ( GLP) and international regulatory guidelines, including OECD, EC, OPPTS and ICH regulatories. These tests comprise gene point mutation tests, chromosomal mutation tests and DNA primary damage tests.
Since 1981, the Genetic Toxicology Laboratory has conducted projects for Human pharmaceutical, chemical, veterinary pharmaceutical, cosmetic, biotechnological, agrochemical, biotech industries and consumer product companies. Our facilities are regularly inspected and Genetic Toxicology Laboratory of IPL is certified by the regulatory authorities/agencies from Europe/ France - AFSSAPS & AFSSA and GIPC.
Concurrently to its contract research activities, the Genetic Toxicology Laboratory of IPL is involved in numerous expertise and research activities including specific research in Nanotoxicology (see below).
List of most relevant experience of the IPL in the field of Nanotoxicology /Genotoxicity of nanoparticles:
Characterization of the determinant physico-chemical properties and establishment of an in vitro model of airway for assessing the genotoxic hazard of nanoparticles from an urban-industrial environment. Project at the regional level, conducted from year 2009 to year 2012 (http://www.nordpasdecalais.fr/sante/appel.asp )
MEGacity Aerosols chemical characterization and TOXicity (MEGATOX Project). With a special attention to the ultra-fine fraction (nanoparticles). Project at the national level (ANR), conducted from year 2009 to year 2012 (http://www.agence-nationale-recherche.fr/documents/aap/2008/selection/ces-2008.pdf )
Fabrice Nesslany, Ph.D.
Deputy Head of Toxicology Laboratory
1 rue du professeur Calmette
BP 245 - F - 59019 Lille Cedex
Tel. +33 20 87 72 72 (direct) / 79 14 (general)
Fax. +33 20 87 79 10
F. NESSLANY was the president of the Working Group Nano3 "Assessment of risks associated with nanomaterials for the general population and the environment" from the French Agency for Environmental and Occupational Health Safety (AFSSET).Last Updated on Wednesday, 22 September 2010 10:06